Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31715742 | 0.89 | NR1H2 (0.40) | EPHX1NR1H2PDE4BHRH3MAPK1 | |
| SCHEMBL1296115 | 0.82 | EPHX1 (0.41) | EPHX1PDE4BGAATP53CYP3A4 | |
| SCHEMBL12892156 | 0.82 | GABRR1 (0.34) | EPHX1GAAHRH3MAPK1HPGD | |
| SCHEMBL12877873 | 0.82 | GABRR1 (0.34) | EPHX1GAAHRH3MAPK1HPGD | |
| SCHEMBL8905563 | 0.81 | EPHX1 (0.33) | EPHX1GAATP53CYP3A4HRH3 | |
| SCHEMBL8788545 | 0.81 | PDE4B (0.34) | EPHX1PDE4BGAATP53CYP3A4 | |
| SCHEMBL30472636 | 0.79 | SLC6A2 (0.40) | TP53CYP3A4PABPC1APOBEC3AAPOBEC3G | |
| SCHEMBL1934486 | 0.79 | SLC6A2 (0.40) | TP53CYP3A4PABPC1APOBEC3AAPOBEC3G | |
| SCHEMBL30472587 | 0.79 | SLC6A2 (0.40) | TP53CYP3A4PABPC1APOBEC3AAPOBEC3G | |
| SCHEMBL28733124 | 0.79 | NR1H2 (0.41) | NR1H2HRH3MAPK1BTKCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11566022-B2 | 3-(5-methoxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof | NOVARTIS AG (CH) | 2023-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11566022-B2 | 3-(5-methoxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof | HBZ, ZFX, HBG1 | EPHX1 2186/4885NR1H2 625/4885PDE4B 4430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.