SCHEMBL24923400

SCHEMBL24923400

CCNC(=O)CNC(=O)C(Cc1ccccc1)NC(=O)CNC(C)=O

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CTSS P25774 3/20 0.55
CTSK P43235 2/20 0.55
OPRD1 P41143 8/20 0.54
OPRM1 P35372 7/20 0.54
OPRK1 P41145 2/20 0.54
CTSL P07711 3/20 0.53
CTSB P07858 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.47
REN P00797 1/20 0.47
CHRNB2 P17787 1/20 0.47
CHRNB4 P30926 1/20 0.47
CHRNA3 P32297 1/20 0.47
CHRNA4 P43681 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25973070 1.00 CTSS (0.55) CTSSCTSKOPRD1OPRM1OPRK1
SCHEMBL27101824 0.90 CTSS (0.53) CTSSCTSKOPRD1OPRM1OPRK1
SCHEMBL29330070 0.89 CTSS (0.52) CTSSCTSKOPRD1OPRM1OPRK1
SCHEMBL18513842 0.89 CTSS (0.54) CTSSCTSKOPRD1OPRM1OPRK1
SCHEMBL4847121 0.87 FCER2 (0.58) CTSSCTSKOPRD1OPRM1OPRK1
SCHEMBL4847134 0.87 FCER2 (0.58) CTSSCTSKOPRD1OPRM1OPRK1
SCHEMBL26559151 0.86 OPRM1 (0.51) CTSSCTSKOPRD1OPRM1OPRK1
SCHEMBL11191376 0.86 ACE (0.56) CTSSCTSKL3MBTL1
SCHEMBL11191380 0.86 ACE (0.56) CTSSCTSKL3MBTL1
SCHEMBL24504162 0.86 OPRD1 (0.64) CTSSCTSKOPRD1OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023006084-A1 ANTI-DLL3 ANTIBODY AND PREPARATION METHOD THEREFOR, DRUG CONJUGATE AND APPLICATION THEREOF 上海复旦张江生物医药股份有限公司 2023-02-02 WO disclosed