Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 5/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.40 |
| ▸ | CHRNB3 | Q05901 | 2/20 | 0.38 |
| ▸ | CHRNA6 | Q15825 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15596226 | 1.00 | CHRNA7 (0.41) | CHRNA7CHRNB4CHRNA3HRH3HTR3A | |
| SCHEMBL16941409 | 1.00 | CHRNA7 (0.41) | CHRNA7CHRNB4CHRNA3HRH3HTR3A | |
| SCHEMBL5939186 | 0.84 | CHRNA7 (0.57) | CHRNA7CHRNB4CHRNA3HTR3ACHRNB2 | |
| SCHEMBL5939192 | 0.84 | CHRNA7 (0.57) | CHRNA7CHRNB4CHRNA3HTR3ACHRNB2 | |
| SCHEMBL5939177 | 0.84 | CHRNA7 (0.57) | CHRNA7CHRNB4CHRNA3HTR3ACHRNB2 | |
| SCHEMBL15596223 | 0.83 | CHRNB2 (0.41) | CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL23605152 | 0.83 | HRH3 (0.44) | CHRNA7CHRNB4CHRNA3HRH3CHRNB2 | |
| SCHEMBL22720980 | 0.82 | SLC6A3 (0.45) | HRH3HTR3ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23605127 | 0.81 | PTGS2 (0.33) | CHRNA7CHRNB4CHRNA3HRH3CHRNB2 | |
| SCHEMBL20696882 | 0.81 | S1PR1 (0.35) | CHRNA7CHRNB4CHRNA3HRH3CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230035837-A1 | ANTIBIOTIC COMPOUNDS, METHODS OF MANUFACTURING THE SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND USES THEREOF | DEBIOPHARM INTERNATIONAL S.A. (CH) | 2023-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230035837-A1 | ANTIBIOTIC COMPOUNDS, METHODS OF MANUFACTURING THE SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND USES THEREOF | GMPS, GNE, GANC | CHRNA7 4721/4885CHRNB4 4842/4885CHRNA3 4833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.