Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.43 |
| ▸ | IL1RN | P18510 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25640385 | 0.80 | ALDH1A1 (0.45) | ALDH1A1SLC6A2SLC6A3KMT2ATDP1 | |
| SCHEMBL30447792 | 0.80 | ALDH1A1 (0.45) | ALDH1A1SLC6A2SLC6A3KMT2ATDP1 | |
| SCHEMBL15394244 | 0.78 | ALDH1A1 (0.40) | ALDH1A1KMT2ATDP1LMNAL3MBTL1 | |
| SCHEMBL5898757 | 0.77 | PSEN1 (0.45) | ALDH1A1SLC6A2SLC6A3KMT2ATDP1 | |
| SCHEMBL18171810 | 0.77 | ALDH1A1 (0.49) | ALDH1A1SLC6A2SLC6A3KMT2ATDP1 | |
| SCHEMBL12640200 | 0.76 | ALDH1A1 (0.64) | ALDH1A1SLC6A2SLC6A3KMT2ATDP1 | |
| SCHEMBL112859 | 0.76 | ALDH1A1 (0.64) | ALDH1A1SLC6A2SLC6A3KMT2ATDP1 | |
| SCHEMBL939536 | 0.76 | ALDH1A1 (0.64) | ALDH1A1SLC6A2SLC6A3KMT2ATDP1 | |
| SCHEMBL24923474 | 0.76 | CYP3A4 (0.43) | ALDH1A1LMNAHPGDNPC1RAB9A | |
| SCHEMBL11063207 | 0.75 | ALDH1A1 (0.50) | ALDH1A1SLC6A2SLC6A3KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230035898-A1 | CYCLODEXTRIN PROTEIN DRUG CONJUGATES | REGENERON PHARMACEUTICALS, INC. | 2023-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230035898-A1 | CYCLODEXTRIN PROTEIN DRUG CONJUGATES | SDCBP, DDOST, KRTCAP2 | ALDH1A1 3824/4885SLC6A2 3717/4885SLC6A3 3578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.