SCHEMBL24923993

SCHEMBL24923993

CC1(C)c2ccccc2N(c2ccc(C#N)cc2-c2nc(-c3ccccc3)nc(-c3cc(C#N)ccc3N3c4ccccc4C(C)(C)c4ccccc43)n2)c2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.40
GABRG2 P18507 1/20 0.40
GABRB3 P28472 1/20 0.40
GABRA5 P31644 1/20 0.40
GABRA3 P34903 1/20 0.40
GABRA2 P47869 1/20 0.40
ABCG2 Q9UNQ0 13/20 0.39
ABCB1 P08183 7/20 0.39
CYP1A2 P05177 3/20 0.37
CYP3A4 P08684 3/20 0.37
MEN1 O00255 2/20 0.37
ALDH1A1 P00352 2/20 0.37
CYP2C19 P33261 2/20 0.37
KMT2A Q03164 2/20 0.37
CLK4 Q9HAZ1 2/20 0.37
CYP2D6 P10635 2/20 0.37
TSHR P16473 2/20 0.37
LMNA P02545 1/20 0.37
CYP2C9 P11712 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24299881 1.00 GABRA1 (0.40) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL27015790 0.94 CYP1A2 (0.40) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL27015879 0.91 PGR (0.39) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL27018625 0.91 GABRG2 (0.38) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL27015947 0.89 PGR (0.39) ABCG2CYP1A2CYP3A4MEN1ALDH1A1
SCHEMBL27015851 0.88 GABRG2 (0.36) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL18361105 0.88 GABRA1 (0.42) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL22916728 0.87 ABCG2 (0.38) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL22147511 0.87 ABCG2 (0.38) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL22147514 0.86 ABCG2 (0.38) GABRA1GABRG2GABRB3GABRA5GABRA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230034026-A1 ORGANIC ELECTROLUMINESCENT DEVICE EMITTING GREEN LIGHT SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-02 US disclosed