Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 2/20 | 0.36 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24676492 | 0.73 | TRPV1 (0.36) | IDH1HCRTR2HCRTR1 | |
| SCHEMBL24923989 | 0.70 | — | — | |
| SCHEMBL8700508 | 0.67 | IDH1 (0.39) | IDH1 | |
| SCHEMBL8700505 | 0.67 | IDH1 (0.39) | IDH1 | |
| SCHEMBL6074316 | 0.67 | IDH1 (0.39) | IDH1 | |
| SCHEMBL14683593 | 0.66 | TRPV3 (0.46) | — | |
| SCHEMBL8879648 | 0.63 | IDH1 (0.32) | IDH1 | |
| SCHEMBL20711403 | 0.63 | TMIGD3 (0.49) | TMIGD3ADORA1HCRTR2HCRTR1 | |
| SCHEMBL24924056 | 0.62 | IDH1 (0.39) | IDH1 | |
| SCHEMBL25271583 | 0.62 | HTR2C (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11560370-B1 | 5-membered heteroaryl carboxamide compounds for treatment of HBV | ASSEMBLY BIOSCIENCES, INC. (US) | 2023-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11560370-B1 | 5-membered heteroaryl carboxamide compounds for treatment of HBV | HCCS, HAVCR2, MAVS | IDH1 38/4885TMIGD3 1059/4885ADORA1 4161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.