Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3928583 | 0.84 | MEN1 (0.50) | MEN1KMT2AGABRA1GABRB1GABRA2 | |
| SCHEMBL16219587 | 0.75 | MEN1 (0.50) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL12836956 | 0.75 | MEN1 (0.43) | MEN1KMT2ADRD2KDM4EALDH1A1 | |
| SCHEMBL16065516 | 0.72 | MEN1 (0.43) | MEN1KMT2ATDP1CA2MAOA | |
| SCHEMBL19679240 | 0.71 | BCL2L1 (0.47) | MEN1KMT2ACYP3A4TSHRTDP1 | |
| SCHEMBL29386169 | 0.71 | BCL2L1 (0.47) | MEN1KMT2ACYP3A4TSHRTDP1 | |
| SCHEMBL30556193 | 0.71 | — | — | |
| SCHEMBL22618624 | 0.67 | BCL2L1 (0.42) | MEN1KMT2ACYP3A4TSHRTDP1 | |
| SCHEMBL29386148 | 0.67 | BCL2L1 (0.42) | MEN1KMT2ACYP3A4TSHRTDP1 | |
| SCHEMBL1524545 | 0.66 | MEN1 (0.38) | MEN1KMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230013959-A1 | COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS | VERBIO SE (DE) | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230013959-A1 | COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS | PRMT6, CYP2D6, POR | MEN1 1230/4885KMT2A 2495/4885GABRA1 3506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.