SCHEMBL3928583

SCHEMBL3928583

Oc1c(Br)cc2c(c1-c1c(O)c(Br)cc3c1CCCC3)CCCC2

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
ALDH1A1 P00352 3/20 0.38
MAPT P10636 3/20 0.38
KDM4E B2RXH2 1/20 0.38
GAA P10253 1/20 0.38
PKM P14618 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
BCL2L1 Q07817 1/20 0.36
BAD Q92934 1/20 0.36
CYP3A4 P08684 2/20 0.36
TSHR P16473 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
MAOA P21397 1/20 0.35
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
GABRA1 P14867 1/20 0.32
GABRB1 P18505 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16219587 0.89 MEN1 (0.50) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL12836956 0.89 MEN1 (0.43) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL16065516 0.85 MEN1 (0.43) MEN1KMT2ATDP1MAOACA2
SCHEMBL24924048 0.84 MEN1 (0.42) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL1524545 0.78 MEN1 (0.38) MEN1KMT2AMAOA
SCHEMBL12793222 0.78 MEN1 (0.38) MEN1KMT2AMAOA
SCHEMBL29488431 0.78 MEN1 (0.38) MEN1KMT2AMAOA
SCHEMBL12057393 0.77 MEN1 (0.61) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL12224023 0.75 MEN1 (0.50) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL14136627 0.74 MEN1 (0.32) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4707264-A2 COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS Verbio SE (DE) 2026-03-11 EP disclosed
EP-4122924-B1 COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS VERBIO SE (DE) 2025-11-19 EP disclosed
US-12065450-B2 Compounds and the use thereof in metathesis reactions VERBIO SE (DE) 2024-08-20 US disclosed
US-11664093-B2 Extrapolative prediction of enantioselectivity enabled by computer-driven workflow, new molecular representations and machine learning THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2023-05-30 US disclosed
US-11664093-B2 Extrapolative prediction of enantioselectivity enabled by computer-driven workflow, new molecular representations and machine learning THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2023-05-30 US disclosed
US-11664093-B2 Extrapolative prediction of enantioselectivity enabled by computer-driven workflow, new molecular representations and machine learning THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2023-05-30 US disclosed
EP-4122924-A2 COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS Verbio Vereinigte BioEnergie AG (DE) 2023-01-25 EP disclosed
US-20230013959-A1 COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS VERBIO SE (DE) 2023-01-19 US disclosed
US-11414446-B1 Compounds and the use thereof in metathesis reactions VERBIO VEREINIGTE BIOENERGIE AG 2022-08-16 US disclosed
EP-3129365-B1 COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS VERBIO VER BIOENERGIE AG (DE) 2022-05-04 EP disclosed
US-20150152332-A1 LIQUID CRYSTAL COMPOSITION, POLYMER, FILM, AND CHOLESTERIC LIQUID CRYSTAL FUJIFILM CORPORATION (JP) 2015-06-04 US disclosed
US-20150152332-A1 LIQUID CRYSTAL COMPOSITION, POLYMER, FILM, AND CHOLESTERIC LIQUID CRYSTAL FUJIFILM CORPORATION (JP) 2015-06-04 US disclosed
US-20120323000-A1 Z-SELECTIVE RING-CLOSING METATHESIS REACTIONS TRUSTEES OF BOSTON COLLEGE (US) 2012-12-20 US disclosed
US-20110065915-A1 CATALYSTS FOR METATHESIS REACTIONS INCLUDING ENANTIOSELECTIVE OLEFIN METATHESIS, AND RELATED METHODS TRUSTEES OF BOSTON COILEGE (MA) 2011-03-17 US disclosed
US-7517828-B2 Chiral broensted acid catalyst for asymmetric synthesis and method of asymmetric synthesis with the catalyst TOAGOSEI CO., LTD. (JP) 2009-04-14 US disclosed
US-20080188657-A1 CHEMICAL PROCESS ASTRAZENECA UK LIMITED (GB) 2008-08-07 US disclosed
US-20080188657-A1 CHEMICAL PROCESS ASTRAZENECA UK LIMITED (GB) 2008-08-07 US disclosed
WO-2008065410-A1 PROCESS FOR THE PREPARATION OF ROSUVASTATIN ASTRAZENECA UK LIMITED (GB) 2008-06-05 WO disclosed
US-20060276329-A1 Asymmetric synthesis catalyst based on chiral brsnsted acid and method of asymmetric synthesis with the catalyst TOAGOSEI CO., LTD. (JP) 2006-12-07 US disclosed
EP-1623971-A1 ASYMMETRIC-SYNTHESIS CATALYST BASED ON CHIRAL BROENSTED ACID AND METHOD OF ASYMMETRIC SYNTHESIS WITH THE CATALYST TOAGOSEI CO., LTD. (JP) 2006-02-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110065915-A1 CATALYSTS FOR METATHESIS REACTIONS INCLUDING ENANTIOSELECTIVE OLEFIN METATHESIS, AND RELATED METHODS SQLE, ICMT, COASY MEN1 729/4885KMT2A 1423/4885ALDH1A1 443/4885
US-20080188657-A1 CHEMICAL PROCESS HMGCR, CYP4A11, ACSL4 MEN1 2050/4885KMT2A 3239/4885ALDH1A1 158/4885
US-11414446-B1 Compounds and the use thereof in metathesis reactions PRMT6, CYP2D6, POR MEN1 1230/4885KMT2A 2495/4885ALDH1A1 1286/4885
US-20120323000-A1 Z-SELECTIVE RING-CLOSING METATHESIS REACTIONS ZYX, ZDHHC7, ZDHHC2 MEN1 432/4885KMT2A 1195/4885ALDH1A1 1620/4885
US-12065450-B2 Compounds and the use thereof in metathesis reactions PRMT6, CYP2D6, POR MEN1 1230/4885KMT2A 2495/4885ALDH1A1 1286/4885
US-20060276329-A1 Asymmetric synthesis catalyst based on chiral brsnsted acid and method of asymmetric synthesis with the catalyst LSS, COASY, FASN MEN1 169/4885KMT2A 2039/4885ALDH1A1 1508/4885
US-20230013959-A1 COMPOUNDS AND THE USE THEREOF IN METATHESIS REACTIONS PRMT6, CYP2D6, POR MEN1 1230/4885KMT2A 2495/4885ALDH1A1 1286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.