SCHEMBL16219587

SCHEMBL16219587

Cc1c(Br)cc2c(c1-c1c(O)c(Br)cc3c1CCCC3)CCCC2

nearest known ligand 0.67

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
MAOA P21397 1/20 0.36
CES1 P23141 2/20 0.33
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
BCL2L1 Q07817 1/20 0.31
BAD Q92934 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3928583 0.89 MEN1 (0.50) MEN1KMT2AMAOACES1KDM4E
SCHEMBL12836956 0.80 MEN1 (0.43) MEN1KMT2ACES1KDM4EALDH1A1
SCHEMBL16065516 0.80 MEN1 (0.43) MEN1KMT2AMAOA
SCHEMBL18868448 0.78 MEN1 (0.35) MEN1KMT2ACES1
SCHEMBL12057393 0.76 MEN1 (0.61) MEN1KMT2AMAOACES1KDM4E
SCHEMBL24924048 0.75 MEN1 (0.42) MEN1KMT2AMAOAKDM4EALDH1A1
SCHEMBL21755083 0.73 MEN1 (0.50) MEN1KMT2AMAOACES1BCL2L1
SCHEMBL1524545 0.73 MEN1 (0.38) MEN1KMT2AMAOA
SCHEMBL29488431 0.73 MEN1 (0.38) MEN1KMT2AMAOA
SCHEMBL12793222 0.73 MEN1 (0.38) MEN1KMT2AMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9776179-B2 Production of fatty olefin derivatives via olefin metathesis PROVIVI, INC. (US) 2017-10-03 US disclosed
US-20170137365-A1 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS PROVIVI, INC. (US) 2017-05-18 US disclosed
US-20140330018-A1 METATHESIS CATALYSTS AND METHODS THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2014-11-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170137365-A1 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS SREBF1, F2, SREBF2 MEN1 348/4885KMT2A 4144/4885MAOA 1786/4885
US-20140330018-A1 METATHESIS CATALYSTS AND METHODS THEREOF TERT, CYP19A1, MPO MEN1 14/4885KMT2A 1441/4885MAOA 202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.