Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 4/20 | 0.41 |
| ▸ | FDPS | P14324 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23740307 | 0.98 | FDPS (0.39) | SMPD1FDPSTSHRTHRBOPRM1 | |
| SCHEMBL435432 | 0.80 | FDPS (0.32) | FDPS | |
| SCHEMBL26831160 | 0.80 | LMNA (0.37) | OPRM1 | |
| SCHEMBL8071809 | 0.79 | OPRM1 (0.42) | SMPD1FDPSTSHRTHRBOPRM1 | |
| SCHEMBL19253997 | 0.79 | OPRM1 (0.42) | SMPD1FDPSTSHRTHRBOPRM1 | |
| SCHEMBL11792783 | 0.79 | OPRM1 (0.42) | SMPD1FDPSTSHRTHRBOPRM1 | |
| SCHEMBL15573847 | 0.79 | OPRM1 (0.42) | SMPD1FDPSTSHRTHRBOPRM1 | |
| SCHEMBL10717958 | 0.78 | FDPS (0.40) | SMPD1FDPSTSHROPRM1DNM1 | |
| SCHEMBL11222814 | 0.78 | SMPD1 (0.38) | SMPD1FDPSTSHRTHRBOPRM1 | |
| SCHEMBL6558334 | 0.77 | FDPS (0.45) | SMPD1FDPSSPHK1GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230033449-A1 | CIRCULATING TUMOR CELL DIAGNOSTICS FOR DETECTION OF NEUROENDOCRINE PROSTATE CANCER (NEPC) | LABORATORY CORPORATION OF AMERICA HOLDINGS | 2023-02-02 | — | — | US | disclosed |