Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 11/20 | 0.35 |
| ▸ | HTR2C | P28335 | 11/20 | 0.35 |
| ▸ | HRH1 | P35367 | 5/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21912850 | 0.74 | ESR1 (0.47) | ABCB1HTR2AHTR2CHRH1ESR1 | |
| SCHEMBL10034876 | 0.71 | ABCB1 (0.37) | ABCB1POLB | |
| SCHEMBL18752234 | 0.69 | ESR1 (0.34) | ABCB1HTR2AHTR2CHRH1ESR1 | |
| SCHEMBL17974163 | 0.69 | ESR1 (0.40) | ABCB1HTR2AHTR2CHRH1ESR1 | |
| SCHEMBL23009876 | 0.68 | ESR1 (0.33) | HTR2AHTR2CHRH1ESR1ESR2 | |
| SCHEMBL27924178 | 0.67 | ABCB1 (0.37) | ABCB1HTR2AHTR2CHRH1ESR1 | |
| SCHEMBL10109661 | 0.67 | ESR1 (0.37) | ABCB1HTR2AHTR2CHRH1ESR1 | |
| SCHEMBL10487772 | 0.66 | ESR1 (0.38) | ABCB1HTR2AHTR2CHRH1ESR1 | |
| SCHEMBL30703071 | 0.66 | POLB (0.44) | ABCB1POLBADRA1A | |
| SCHEMBL21500047 | 0.64 | NR3C1 (0.34) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11560394-B2 | Metal complex comprising amidine and indole fused cyclopentadienyl ligands | ARLANXEO NETHERLANDS B.V. | 2023-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11560394-B2 | Metal complex comprising amidine and indole fused cyclopentadienyl ligands | C5, C1S, CLIC4 | ABCB1 4215/4885HTR2A 185/4885HTR2C 264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.