SCHEMBL2492428

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2491478	0.92	CYP1A2 (0.48)	PDE5APDE4APDE4BPDE4CPDE4D
	SCHEMBL2491572	0.87	ALDH1A1 (0.43)	PDE5AKDM4EALDH1A1MAPTHPGD
	SCHEMBL2494385	0.86	HTR7 (0.45)	PDE5APDE4APDE4BPDE4CPDE4D
	SCHEMBL10438816	0.82	HTR7 (0.53)	PDE5APDE4APDE4BPDE4CPDE4D
	SCHEMBL1835625	0.82	PDE5A (0.42)	PDE5APDE4APDE4BPDE4CPDE4D
	SCHEMBL815746	0.79	CYP1A2 (0.47)	CYP1A2CYP2C9CYP2C19MCHR1KDM4E
	SCHEMBL2489513	0.78	CYP1A2 (0.53)	PDE5APDE4APDE4BPDE4CPDE4D
	SCHEMBL2027108	0.78	APP (0.50)	HTR7KDM4EMEN1USP2ALDH1A1
	SCHEMBL1837903	0.74	CYP1A2 (0.49)	PDE5APDE4APDE4BPDE4CPDE4D
	SCHEMBL2253647	0.74	CHRM2 (0.49)	CYP1A2CYP2C9CYP2C19MCHR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.