Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL816441 | 0.89 | CYP1A2 (0.60) | CYP1A2CYP2C19CYP2C9HTR2BTLR8 | |
| SCHEMBL5417465 | 0.88 | CYP2C9 (0.53) | CYP1A2CYP2C19CYP2C9HTR2BTLR8 | |
| SCHEMBL7331060 | 0.86 | MEN1 (0.54) | CYP1A2CYP2C19CYP2C9HTR2BTLR8 | |
| SCHEMBL20873606 | 0.86 | MEN1 (0.54) | CYP1A2CYP2C19CYP2C9HTR2BTLR8 | |
| SCHEMBL1272187 | 0.86 | MEN1 (0.54) | CYP1A2CYP2C19CYP2C9HTR2BTLR8 | |
| SCHEMBL10857424 | 0.86 | MEN1 (0.54) | CYP1A2CYP2C19CYP2C9HTR2BTLR8 | |
| SCHEMBL8847317 | 0.86 | MEN1 (0.54) | CYP1A2CYP2C19CYP2C9HTR2BTLR8 | |
| SCHEMBL7283843 | 0.86 | MEN1 (0.54) | CYP1A2CYP2C19CYP2C9HTR2BTLR8 | |
| SCHEMBL41192 | 0.86 | MEN1 (0.54) | CYP1A2CYP2C19CYP2C9HTR2BTLR8 | |
| SCHEMBL2494385 | 0.84 | HTR7 (0.45) | CYP1A2CYP2C19CYP2C9HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210087163-A1 | PHENOXY THIOPHENE SULFONAMIDES AND OTHER COMPOUNDS FOR USE AS INHIBITORS OF BACTERIAL GLUCURONIDASE | NORTH CAROLINA CENTRAL UNIVERSITY (US) | 2021-03-25 | — | — | US | claimed |
| EP-2544535-B1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE AS INHIBITORS OF GLUCURONIDASE | NORTH CAROLINA CENTRAL UNIV (US) | 2017-04-19 | — | — | EP | claimed |
| US-20160237058-A1 | PHENOXY THIOPHENE SULFONAMIDES AND OTHER COMPOUNDS FOR USE AS INHIBITORS OF BACTERIAL GLUCURONIDASE | NORTH CAROLINA CENTRAL UNIVERSITY (US) | 2016-08-18 | — | — | US | claimed |
| US-20130345196-A1 | PHENOXY THIOPHENE SULFONAMIDES AND OTHER COMPOUNDS FOR USE AS INHIBITORS OF BACTERIAL GLUCURONIDASE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2013-12-26 | — | — | US | claimed |
| US-20130345235-A1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE AS INHIBITORS OF GLUCURONIDASE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2013-12-26 | — | — | US | claimed |
| EP-2544535-A1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE AS INHIBITORS OF GLUCURONIDASE | North Carolina Central University (US) | 2013-01-16 | — | — | EP | claimed |
| WO-2011112858-A1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE AS INHIBITORS OF GLUCURONIDASE | NORTH CAROLINA CENTRAL UNIVERSITY (US) | 2011-09-15 | — | — | WO | claimed |
| WO-2011084503-A1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | NORTH CAROLINA CENTRAL UNIVERSITY (US) | 2011-07-14 | — | — | WO | claimed |
| US-7247687-B2 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-07-24 | — | — | US | claimed |
| EP-1521758-B1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2006-05-24 | — | — | EP | claimed |
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-03-02 | — | — | US | claimed |
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | claimed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | claimed |
| US-5885548-A | Multiply substituted DTPA derivatives and their metal complexes, and their metal complexes, pharmaceutical agents that contain these complexes, their use in diagnosis and therapy, as well as process for the production of pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-03-23 | — | — | US | claimed |
| US-5746995-A | DTPA derivatives substituted in a novel way, their metal complexes, and their use in diagnosis and therapy | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-05-05 | — | — | US | claimed |
| EP-0752622-A1 | Acetal polymers useful in photosensitive compositions | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-01-08 | — | — | EP | claimed |
| US-5534381-A | POLYMERS FOR LITHOGRAPHIC PRINTING PLATES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-07-09 | — | — | US | claimed |
| US-4591376-A | PLANT GROWTH REGULATORS | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-05-27 | — | — | US | claimed |
| EP-0126234-A2 | 1,2,3-Thiadiazol-3-in-5-ylidene ureas, their preparation and compositions as plant-growth regulators and defoliants | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-11-28 | — | — | EP | claimed |
| US-3940395-A | CNS DEPRESSANT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-02-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | MLX, LOX, LMTK3 | CYP1A2 2390/4885CYP2C19 3676/4885CYP2C9 3617/4885 |
| US-20130345235-A1 | PHENOXY THIOPHENE SULFONAMIDES AND THEIR USE AS INHIBITORS OF GLUCURONIDASE | CES2, TOP1, GUSB | CYP1A2 310/4885CYP2C19 431/4885CYP2C9 155/4885 |
| US-20160237058-A1 | PHENOXY THIOPHENE SULFONAMIDES AND OTHER COMPOUNDS FOR USE AS INHIBITORS OF BACTERIAL GLUCURONIDASE | TOP2A, TOP1, PNP | CYP1A2 134/4885CYP2C19 303/4885CYP2C9 156/4885 |
| US-20130345196-A1 | PHENOXY THIOPHENE SULFONAMIDES AND OTHER COMPOUNDS FOR USE AS INHIBITORS OF BACTERIAL GLUCURONIDASE | TOP2A, TOP1, TOP2B | CYP1A2 103/4885CYP2C19 267/4885CYP2C9 140/4885 |
| US-20210087163-A1 | PHENOXY THIOPHENE SULFONAMIDES AND OTHER COMPOUNDS FOR USE AS INHIBITORS OF BACTERIAL GLUCURONIDASE | TOP2A, TOP1, PNP | CYP1A2 134/4885CYP2C19 303/4885CYP2C9 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.