Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | CBLB | Q13191 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | JMJD1C | Q15652 | 1/20 | 0.34 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24925529 | 0.85 | P2RX7 (0.49) | SYKCBLBKDM4EKDM5AJMJD1C | |
| SCHEMBL24714543 | 0.82 | ALDH1A1 (0.35) | SYKCBLBKDM4EKDM5AJMJD1C | |
| SCHEMBL24714547 | 0.81 | CNR1 (0.44) | SYKKDM4ELMNASMN1; SMN2 | |
| SCHEMBL2627832 | 0.80 | KDM4E (0.49) | KDM4DSYKKDM4EKDM5AJMJD1C | |
| SCHEMBL13043849 | 0.80 | ALDH1A1 (0.42) | KDM4DSYKKDM4EKDM5AJMJD1C | |
| SCHEMBL31506349 | 0.80 | KDM4E (0.49) | KDM4DSYKKDM4EKDM5AJMJD1C | |
| SCHEMBL3683998 | 0.79 | SYK (0.41) | SYKKDM4EKDM5AJMJD1CKDM3A | |
| SCHEMBL13043958 | 0.79 | GABRP (0.35) | KDM4DSYKKDM4EKDM5AJMJD1C | |
| SCHEMBL3743806 | 0.79 | KDM4E (0.47) | KDM4DSYKKDM4EKDM5AJMJD1C | |
| SCHEMBL24925458 | 0.77 | KDM4E (0.35) | KDM4DSYKKDM4EKDM5AJMJD1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230022696-A1 | SMALL MOLECULE INHIBITORS OF AUTOPHAGY AND HISTONE DEACTYLASES AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230022696-A1 | SMALL MOLECULE INHIBITORS OF AUTOPHAGY AND HISTONE DEACTYLASES AND USES THEREOF | HDAC5, HDAC4, HDAC7 | HDAC1 5/4885HDAC8 10/4885KDM4D 395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.