Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.50 |
| ▸ | REN | P00797 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 3/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | YAP1 | P46937 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6780588 | 0.85 | CTSS (0.54) | KLK5CTSSCTSKCTSLCTSB | |
| SCHEMBL7292396 | 0.85 | CACNA1B (0.60) | KLK5CACNA1BCTSSCTSKCTSL | |
| SCHEMBL6438287 | 0.85 | CACNA1B (0.60) | KLK5CACNA1BCTSSCTSKCTSL | |
| SCHEMBL9240969 | 0.85 | CACNA1B (0.60) | KLK5CACNA1BCTSSCTSKCTSL | |
| SCHEMBL23331990 | 0.84 | CACNA1B (0.47) | KLK5CACNA1BRENCTSSCTSK | |
| SCHEMBL23306678 | 0.84 | CACNA1B (0.47) | KLK5CACNA1BRENCTSSCTSK | |
| SCHEMBL85543 | 0.84 | CTSS (0.64) | KLK5CTSSCTSKCTSLCTSB | |
| SCHEMBL22404737 | 0.84 | CTSS (0.64) | KLK5CTSSCTSKCTSLCTSB | |
| SCHEMBL3355326 | 0.84 | CTSS (0.64) | KLK5CTSSCTSKCTSLCTSB | |
| SCHEMBL23331994 | 0.83 | CTSS (0.54) | KLK5CTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230025922-A1 | USE OF ITACONATE AND ITS DERIVATIVES/ANALOGUES TO INDUCE HAIR GROWTH | THE JOHNS HOPKINS UNIVERSTY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230025922-A1 | USE OF ITACONATE AND ITS DERIVATIVES/ANALOGUES TO INDUCE HAIR GROWTH | LRBA, HADHA, IMPDH1 | KLK5 2230/4885CACNA1B 4762/4885REN 3897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.