Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL7755505 | 0.87 | GABRA1 (0.43) | GABRA1GABRB2MAPTNPSR1L3MBTL1 | |
| SCHEMBL498530 | 0.86 | GABRA1 (0.44) | GABRA1GABRB2MAPTNPSR1L3MBTL1 | |
| SCHEMBL8750546 | 0.82 | L3MBTL1 (0.44) | GABRA1GABRB2MAPTNPSR1L3MBTL1 | |
| Di(Hydroxyethyl)Ether SCHEMBL11297658 | 0.82 | TSHR (0.39) | GABRA1GABRB2MAPTNPSR1L3MBTL1 | |
| SCHEMBL23343755 | 0.78 | MAOB (0.46) | ALDH1A1 | |
| SCHEMBL9789585 | 0.78 | L3MBTL1 (0.46) | GABRA1GABRB2L3MBTL1PTPRCPTPN1 | |
| SCHEMBL1411710 | 0.77 | GABRA1 (0.46) | GABRA1GABRB2MAPTNPSR1L3MBTL1 | |
| SCHEMBL14394524 | 0.77 | TSHR (0.62) | MAPTL3MBTL1ALDH1A1GAAHTT | |
| SCHEMBL2792022 | 0.77 | GABRA1 (0.44) | GABRA1GABRB2MAPTNPSR1L3MBTL1 | |
| SCHEMBL7232096 | 0.76 | GABRA1 (0.38) | GABRA1GABRB2MAPTNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230019032-A1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230019032-A1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | MAPK1, ALK, MAP3K1 | GABRA1 2882/4885GABRB2 4079/4885MAPT 458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.