Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 5/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.43 |
| ▸ | BTK | Q06187 | 2/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29131876 | 0.92 | IL1B (0.42) | IL1BNLRP3BTKSMOKCNH2 | |
| SCHEMBL29131878 | 0.92 | IL1B (0.42) | IL1BNLRP3BTKSMOKCNH2 | |
| SCHEMBL29131886 | 0.88 | IL1B (0.54) | IL1BNLRP3KCNH2 | |
| SCHEMBL29275818 | 0.88 | IL1B (0.54) | IL1BNLRP3KCNH2 | |
| SCHEMBL29131880 | 0.88 | IL1B (0.54) | IL1BNLRP3KCNH2 | |
| SCHEMBL28961895 | 0.80 | IL1B (0.61) | IL1BNLRP3BTKKCNH2 | |
| SCHEMBL29275955 | 0.80 | IL1B (0.61) | IL1BNLRP3BTKKCNH2 | |
| SCHEMBL28963147 | 0.80 | HCRTR1 (0.43) | IL1BNLRP3BTKSMO | |
| SCHEMBL28963149 | 0.80 | HCRTR1 (0.43) | IL1BNLRP3BTKSMO | |
| SCHEMBL29131965 | 0.79 | CHEK1 (0.43) | IL1BNLRP3KCNH2CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023003002-A1 | ANNULATED PYRIDAZINE COMPOUND | アステラス製薬株式会社 | 2023-01-26 | — | — | WO | disclosed |