Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 5/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.41 |
| ▸ | SMO | Q99835 | 2/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29131876 | 1.00 | IL1B (0.42) | IL1BNLRP3SMOLOXL2LOX | |
| SCHEMBL24925909 | 0.92 | IL1B (0.43) | IL1BNLRP3SMOBTKKCNH2 | |
| SCHEMBL29131886 | 0.87 | IL1B (0.54) | IL1BNLRP3KCNH2 | |
| SCHEMBL29275818 | 0.87 | IL1B (0.54) | IL1BNLRP3KCNH2 | |
| SCHEMBL29131880 | 0.87 | IL1B (0.54) | IL1BNLRP3KCNH2 | |
| SCHEMBL28963149 | 0.86 | HCRTR1 (0.43) | IL1BNLRP3SMOBTKPBRM1 | |
| SCHEMBL28963147 | 0.86 | HCRTR1 (0.43) | IL1BNLRP3SMOBTKPBRM1 | |
| SCHEMBL29131901 | 0.80 | IL1B (0.59) | IL1BNLRP3SMOBTKKCNH2 | |
| SCHEMBL25403629 | 0.80 | IL1B (0.44) | IL1BNLRP3SMOKCNH2LIPG | |
| SCHEMBL29131905 | 0.80 | IL1B (0.59) | IL1BNLRP3SMOBTKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969920-A | Fused pyridazine derivative, preparation method and medical application thereof | 上海辉启生物医药科技有限公司 | 2023-10-31 | — | — | CN | disclosed |