SCHEMBL24927667

SCHEMBL24927667

N#Cc1ccc(-c2cccc(C#N)c2-c2c3ccccc3c(-c3ccccc3)c3ccccc23)cc1-n1c2ccccc2c2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SSTR2 P30874 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
HIF1A Q16665 1/20 0.34
MAOA P21397 1/20 0.33
TRPA1 O75762 1/20 0.33
ALDH1A1 P00352 5/20 0.33
KDM4E B2RXH2 4/20 0.33
LMNA P02545 3/20 0.33
AR P10275 2/20 0.33
HTT P42858 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
THRB P10828 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MCL1 Q07820 1/20 0.32
HPGD P15428 3/20 0.32
MAPK1 P28482 1/20 0.32
CYP19A1 P11511 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24926979 0.93 SSTR2 (0.35) SSTR2SMN1; SMN2HIF1AMAOATRPA1
SCHEMBL24926914 0.91 KDM4E (0.34) SMN1; SMN2HIF1AMAOAALDH1A1KDM4E
SCHEMBL24927073 0.90 KDM4E (0.36) SMN1; SMN2MAOAALDH1A1KDM4ELMNA
SCHEMBL24927318 0.89 AR (0.35) SMN1; SMN2MAOATRPA1ALDH1A1KDM4E
SCHEMBL24927109 0.88 KDM4E (0.34) SMN1; SMN2MAOAALDH1A1KDM4ELMNA
SCHEMBL24927220 0.88 AR (0.34) SMN1; SMN2MAOATRPA1ALDH1A1KDM4E
SCHEMBL24927273 0.88 KDM4E (0.41) SSTR2SMN1; SMN2HIF1AMAOAALDH1A1
SCHEMBL24927471 0.87 KDM4E (0.41) SSTR2SMN1; SMN2HIF1AALDH1A1KDM4E
SCHEMBL22377763 0.87 IMPDH2 (0.35) SSTR2SMN1; SMN2HIF1ATRPA1ALDH1A1
SCHEMBL24927132 0.87 CYP11B1 (0.37) SMN1; SMN2HIF1AMAOAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301179-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-21 US disclosed
US-20230174560-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-08 US disclosed
US-20230165130-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-25 US disclosed
US-20230034532-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230165130-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE HETEROCYCLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE CYP1A1, CYP2E1, AOX1 SSTR2 2909/4885SMN1; SMN2 3587/4885HIF1A 1875/4885
US-20230174560-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE CRY1, AOX1, CYP1A1 SSTR2 3485/4885SMN1; SMN2 3740/4885HIF1A 1897/4885
US-20230034532-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME NR0B1, CRY1, CCNT1 SSTR2 2614/4885SMN1; SMN2 3122/4885HIF1A 865/4885
US-20230301179-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE CRY1, AOX1, CYP1A1 SSTR2 3552/4885SMN1; SMN2 3710/4885HIF1A 1871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.