SCHEMBL24927992

SCHEMBL24927992

Cc1nc(C)c(C2(CN)NC(=O)NC2=O)s1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADAMTS7 Q9UKP4 1/20 0.33
ADAM17 P78536 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL23354105 0.98 ADAMTS7 (0.33) ADAMTS7ADAM17
Hydrochloric Acid SCHEMBL29979629 0.98 ADAMTS7 (0.33) ADAMTS7ADAM17
Hydrochloric Acid SCHEMBL29980219 0.82 ADAMTS7 (0.32) ADAMTS7
SCHEMBL23371329 0.82 ADAMTS7 (0.44) ADAMTS7ADAM17
Hydrochloric Acid SCHEMBL23354184 0.81 ADAMTS7 (0.43) ADAMTS7ADAM17
Hydrochloric Acid SCHEMBL31676887 0.81 ADAMTS7 (0.43) ADAMTS7ADAM17
SCHEMBL23354019 0.79 ADAMTS7 (0.43) ADAMTS7ADAM17
SCHEMBL31676866 0.76 ADAM17 (0.35) ADAMTS7ADAM17
SCHEMBL23361634 0.76 ADAM17 (0.35) ADAMTS7ADAM17
Hydrochloric Acid SCHEMBL23353990 0.75 ADAM17 (0.34) ADAMTS7ADAM17

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230027346-A1 SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS BAYER AKTIENGESELLSCHAFT (DE) 2023-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230027346-A1 SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS ADAMTS7, MMP7, ADAM17 ADAMTS7 1/4885ADAM17 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.