SCHEMBL2492869

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2493412	0.83	IDO1 (0.50)	IDO1KDM4EGLAALDH1A1HPGD
	SCHEMBL2001238	0.83	FABP4 (0.48)	IDO1FABP4KDM4EGLAJAK2
	SCHEMBL184136	0.81	ALDH1A1 (0.62)	FABP4KDM4EALDH1A1HPGDHSD17B10
	SCHEMBL2557198	0.81	IDO1 (0.43)	IDO1FABP4KDM4EGLAJAK2
	SCHEMBL18967133	0.81	IDO1 (0.43)	IDO1FABP4KDM4EGLAJAK2
	SCHEMBL6088062	0.81	JAK2 (0.48)	IDO1FABP4KDM4EGLAJAK2
	SCHEMBL526384	0.80	IDO1 (0.52)	IDO1FABP4ALDH1A1CYP3A4TSHR
	Water SCHEMBL8638678	0.79	IDO1 (0.42)	IDO1FABP4KDM4EGLAJAK2
	SCHEMBL2493442	0.79	TSHR (0.50)	KDM4EGLAALDH1A1HPGDHSD17B10
	Water SCHEMBL1144744	0.79	IDO1 (0.42)	IDO1FABP4KDM4EGLAJAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.