SCHEMBL24928948

SCHEMBL24928948

Cc1oncc1-c1cc(NSc2cc(C(=O)O)ccc2C2CC2)c(OC2CC(F)(F)C2)cc1Cl

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24930076 0.91 LRRK2 (0.33)
SCHEMBL30153306 0.86 ACLY (0.36)
SCHEMBL24928850 0.86 ACLY (0.36)
SCHEMBL24928945 0.82
SCHEMBL22647965 0.79 CREBBP (0.33) NR1H4
SCHEMBL22647973 0.78 NTRK1 (0.35)
SCHEMBL31198500 0.76 ACLY (0.38)
SCHEMBL24928843 0.76 ACLY (0.38)
SCHEMBL24928651 0.76 ACLY (0.38)
SCHEMBL30153324 0.76 ACLY (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023007188-A1 PHENYL-SULFAMOYL-BENZOIC ACID DERIVATIVES AS ERAP1- MODULATORS Grey Wolf Therapeutics Limited (GB) 2023-02-02 WO disclosed