Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 10/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 8/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | LOX | P28300 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | EIF4E | P06730 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24930069 | 0.85 | CSNK2A1 (0.39) | MCHR1CHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL24928863 | 0.82 | CSNK2A1 (0.36) | MCHR1CHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL30845564 | 0.82 | CYP19A1 (0.35) | FEN1ALOX5APPLAT | |
| SCHEMBL24928670 | 0.78 | PDE4A (0.38) | MCHR1CSNK2A1PDE4AMKNK1MKNK2 | |
| SCHEMBL24928930 | 0.72 | — | — | |
| SCHEMBL19643299 | 0.71 | CSNK2A1 (0.36) | FEN1ALOX5APMCHR1CSNK2A1PDE4A | |
| SCHEMBL24929568 | 0.69 | BRD4 (0.33) | FEN1ALOX5AP | |
| SCHEMBL30845559 | 0.68 | BCL6 (0.37) | CSNK2A1 | |
| SCHEMBL24928929 | 0.68 | CSNK2A1 (0.34) | CSNK2A1PDE4A | |
| SCHEMBL22637224 | 0.66 | ALDH1A1 (0.38) | CHEK1CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881657-A | Phenyl-sulfamoyl-benzoic acid derivatives as ERAP1 modulators | 格雷沃尔夫治疗有限公司 | 2024-04-12 | — | — | CN | disclosed |
| WO-2023007188-A1 | PHENYL-SULFAMOYL-BENZOIC ACID DERIVATIVES AS ERAP1- MODULATORS | Grey Wolf Therapeutics Limited (GB) | 2023-02-02 | — | — | WO | disclosed |