SCHEMBL24928929

SCHEMBL24928929

O=Nc1cc(-c2ccns2)c(Cl)cc1OC1CCCC1

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 2/20 0.34
KMO O15229 6/20 0.34
HPGD P15428 1/20 0.33
PDE4A P27815 3/20 0.31
PDE4B Q07343 3/20 0.31
PDE4C Q08493 3/20 0.31
PDE4D Q08499 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24930069 0.82 CSNK2A1 (0.39) CSNK2A1KMOHPGDPDE4APDE4B
SCHEMBL24928863 0.80 CSNK2A1 (0.36) CSNK2A1KMOHPGD
SCHEMBL30845559 0.80 BCL6 (0.37) CSNK2A1KMOHPGD
SCHEMBL24928654 0.68 ACLY (0.37) PDE4APDE4BPDE4CPDE4D
SCHEMBL31198454 0.68 ACLY (0.37) PDE4APDE4BPDE4CPDE4D
SCHEMBL24929104 0.68 FEN1 (0.38) CSNK2A1PDE4A
SCHEMBL24928930 0.67
SCHEMBL24928715 0.66 ACLY (0.37)
SCHEMBL30845564 0.66 CYP19A1 (0.35) PDE4B
SCHEMBL24928670 0.65 PDE4A (0.38) CSNK2A1KMOPDE4APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023007188-A1 PHENYL-SULFAMOYL-BENZOIC ACID DERIVATIVES AS ERAP1- MODULATORS Grey Wolf Therapeutics Limited (GB) 2023-02-02 WO disclosed