Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | AHR | P35869 | 2/20 | 0.34 |
| ▸ | NQO1 | P15559 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4429087 | 0.82 | CYP2D6 (0.42) | ALDH1A1SMN1; SMN2MAOATAAR1KMT2A | |
| SCHEMBL450881 | 0.80 | KDM4E (0.38) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL9383291 | 0.80 | KDM4E (0.42) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL19752534 | 0.78 | TAAR1 (0.35) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL23287877 | 0.74 | CYP2B6 (0.31) | TDP1L3MBTL1 | |
| SCHEMBL30670233 | 0.73 | KDM4E (0.44) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL4711831 | 0.73 | TDP1 (0.49) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL4619985 | 0.73 | KDM4E (0.44) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL271403 | 0.73 | KDM4E (0.44) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL2243434 | 0.73 | KDM4E (0.35) | KDM4EALDH1A1HPGDMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805268-B | Synthesis method of visible light mediated cyclopenta [ b ] benzofuran derivative | 河南大学 | 2024-03-08 | — | — | CN | claimed |
| CN-114805268-A | Synthesis method of visible light mediated cyclopenta [ b ] benzofuran derivative | 河南大学 | 2022-07-29 | — | — | CN | claimed |
| EP-1303520-A4 | THERAPEUTIC COMPOUNDS AND METHODS | GOVERNMENT OF THE STATE OF SAR (MY) | 2005-03-30 | — | — | EP | claimed |
| EP-1303520-A1 | THERAPEUTIC COMPOUNDS AND METHODS | The Government of the State of Sarawak, Malaysia (MY) | 2003-04-23 | — | — | EP | claimed |
| WO-2002002566-A1 | THERAPEUTIC COMPOUNDS AND METHODS | THE GOVERNMENT OF THE STATE OF SARAWAK, MALAYSIA (MY) | 2002-01-10 | — | — | WO | claimed |
| EP-0463162-A1 | PREPARATION OF 5,6,7-TRINOR-4,8-INTER-m-PHENYLENE PGI 2 DERIVATIVES | TORAY INDUSTRIES, INC. (JP) | 1992-01-02 | — | — | EP | claimed |
| JP-2200652-A | — | — | None | — | — | JP | disclosed |
| US-20260146034-A1 | 1H-CYCLOPENTA[B]BENZOFURAN DERIVATIVES FOR THE PREVENTION AND TREATMENT OF VIRUS DISEASES | SJP BIOTEC GMBH (CH) | 2026-05-28 | — | — | US | disclosed |
| US-20260146034-A1 | 1H-CYCLOPENTA[B]BENZOFURAN DERIVATIVES FOR THE PREVENTION AND TREATMENT OF VIRUS DISEASES | SJP BIOTEC GMBH (CH) | 2026-05-28 | — | — | US | disclosed |
| US-20260146034-A1 | 1H-CYCLOPENTA[B]BENZOFURAN DERIVATIVES FOR THE PREVENTION AND TREATMENT OF VIRUS DISEASES | SJP BIOTEC GMBH (CH) | 2026-05-28 | — | — | US | disclosed |
| US-12612395-B2 | Rocaglate derivatives and uses thereof | TRUSTEES OF BOSTON UNIVERSITY (US) | 2026-04-28 | — | — | US | disclosed |
| EP-4687879-A1 | COMPOUNDS FOR THE TREATMENT AND PREVENTION OF VIRAL DISEASES | SJP Biotec GmbH (CH) | 2026-02-11 | — | — | EP | disclosed |
| EP-4687879-A1 | COMPOUNDS FOR THE TREATMENT AND PREVENTION OF VIRAL DISEASES | SJP Biotec GmbH (CH) | 2026-02-11 | — | — | EP | disclosed |
| EP-0232776-A2 | 2,5,6,7-tetranor-4,8-inter-m-phenylene PGI2 derivatives | TORAY INDUSTRIES, INC. (JP) | 1987-08-19 | — | — | EP | disclosed |
| EP-0084856-B1 | 5,6,7-TRINOR-4, 8-INTER-M-PHENYLENE PROSTAGLANDIN I2 DERIVATIVES | TORAY INDUSTRIES, INC. (JP) | 1986-11-20 | — | — | EP | disclosed |
| US-4564620-A | 5,6,7,-Trinor-4,8-inter-m-phenylene PGI2 derivatives and anti-ulcer, anti-thrombotic and anti-hypertensive pharmaceutical compositions containing them | TORAY INDUSTRIES, INC. (JP) | 1986-01-14 | — | — | US | disclosed |
| US-4539414-A | ANTILEUKEMIA AGENTS | MING LU KING (TW) | 1985-09-03 | — | — | US | disclosed |
| US-4539414-A | ANTILEUKEMIA AGENTS | MING LU KING (TW) | 1985-09-03 | — | — | US | disclosed |
| US-4474802-A | 5,6,7-Trinor-4,8-inter-m-phenylene prostaglandin I2 derivatives useful in anti-ulcer, hypotensive and platelet aggregation inhibiting compositions | TORAY INDUSTRIES, INC. (JP) | 1984-10-02 | — | — | US | disclosed |
| EP-0084856-A1 | 5,6,7-Trinor-4, 8-inter-m-phenylene prostaglandin I2 derivatives | TORAY INDUSTRIES, INC. (JP) | 1983-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12612395-B2 | Rocaglate derivatives and uses thereof | GLRB, SRR, HCAR3 | KDM4E 3241/4885ALDH1A1 715/4885HPGD 1791/4885 |
| US-20260146034-A1 | 1H-CYCLOPENTA[B]BENZOFURAN DERIVATIVES FOR THE PREVENTION AND TREATMENT OF VIRUS DISEASES | NSUN2, NSUN3, ZC3HAV1 | KDM4E 3666/4885ALDH1A1 1304/4885HPGD 4730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.