Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMYD3 | Q9H7B4 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30239064 | 1.00 | ALDH1A1 (0.51) | ALDH1A1HTTKMT2AMAPTNPC1 | |
| SCHEMBL24931201 | 0.91 | ALDH1A1 (0.51) | ALDH1A1HTTKMT2AMAPTNPC1 | |
| SCHEMBL30239149 | 0.91 | ALDH1A1 (0.51) | ALDH1A1HTTKMT2AMAPTNPC1 | |
| SCHEMBL30239130 | 0.90 | ALDH1A1 (0.47) | ALDH1A1HTTKMT2AMAPTNPC1 | |
| SCHEMBL30239120 | 0.86 | ALDH1A1 (0.52) | ALDH1A1HTTKMT2AMAPTNPC1 | |
| SCHEMBL10575185 | 0.82 | ACHE (0.49) | ALDH1A1HTTMAPTCYP1A2CYP2C9 | |
| SCHEMBL2218702 | 0.80 | MAPT (0.72) | ALDH1A1HTTKMT2AMAPTNPC1 | |
| SCHEMBL10573468 | 0.80 | ACHE (0.49) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6919274 | 0.79 | MEN1 (0.48) | ALDH1A1KMT2AMAPTHPGDCYP1A2 | |
| SCHEMBL2228741 | 0.79 | MAPT (0.70) | ALDH1A1HTTKMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023003973-A1 | INHIBITORS TARGETING UBIQUITIN SPECIFIC PROTEASE 7 (USP7) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-01-26 | — | — | WO | disclosed |