Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 5/20 | 0.44 |
| ▸ | ACHE | P22303 | 5/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10573468 | 0.86 | ACHE (0.49) | ALDH1A1KDM4EMAPTCYP1A2CYP2C19 | |
| SCHEMBL9382303 | 0.85 | MEN1 (0.65) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL10575185 | 0.83 | ACHE (0.49) | ALDH1A1KDM4EMAPTCYP1A2CYP2C19 | |
| SCHEMBL16210432 | 0.81 | PDE5A (0.56) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL21940782 | 0.80 | MEN1 (0.46) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL21939917 | 0.80 | CHRNA7 (0.43) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL16401275 | 0.80 | BAZ2B (0.48) | MAPTLMNA | |
| SCHEMBL24931199 | 0.79 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL30239064 | 0.79 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL6606481 | 0.79 | KMT2A (0.76) | MEN1KMT2AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067513-A1 | ANTAGONISTS FOR ALPHA-2 ADRENOCEPTORS | OY JUVANTIA PHARMA LTD (FI) | 2004-08-12 | — | — | WO | disclosed |
| US-5602142-A | PROMOTER FOR IMPROVING RADIOSENSITIZATION AND CHEMOSENSITIZATION | EVANSTON HOSPITAL CORPORATION (US) | 1997-02-11 | — | — | US | disclosed |