Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.48 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30240716 | 1.00 | SIRT2 (0.48) | SIRT2SIRT3DHODHMAOBSIRT1 | |
| SCHEMBL24933661 | 0.89 | MAOB (0.42) | SIRT2SIRT3DHODHMAOBSIRT1 | |
| SCHEMBL24933346 | 0.88 | MAOB (0.41) | MAOBNPC1RAB9A | |
| SCHEMBL30240693 | 0.88 | MAOB (0.41) | MAOBNPC1RAB9A | |
| SCHEMBL24933199 | 0.85 | MAOB (0.46) | MAOBNPC1RAB9A | |
| SCHEMBL30896275 | 0.85 | LMNA (0.45) | SIRT2DHODHSIRT1NPC1RAB9A | |
| SCHEMBL30240807 | 0.85 | MAOB (0.46) | MAOBNPC1RAB9A | |
| SCHEMBL24933362 | 0.85 | MAOB (0.47) | MAOBMAPTL3MBTL1 | |
| SCHEMBL24933615 | 0.85 | MAOB (0.60) | MAOBMAPTL3MBTL1 | |
| SCHEMBL24932976 | 0.85 | MAOB (0.52) | MAOBNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |