Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 15/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 12/20 | 0.50 |
| ▸ | BTK | Q06187 | 2/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24933312 | 0.88 | BTK (0.42) | HSD17B2HSD17B1BTKCDC7ALDH1A1 | |
| SCHEMBL24933605 | 0.88 | HSD17B2 (0.41) | HSD17B2HSD17B1 | |
| SCHEMBL24933339 | 0.86 | HSD17B1 (0.41) | HSD17B2HSD17B1BTKCDC7 | |
| SCHEMBL24932950 | 0.86 | HSD17B2 (0.52) | HSD17B2HSD17B1CDC7ALDH1A1HPGD | |
| SCHEMBL24933754 | 0.86 | HSD17B2 (0.53) | HSD17B2HSD17B1CDC7 | |
| SCHEMBL30896148 | 0.86 | HSD17B2 (0.53) | HSD17B2HSD17B1CDC7 | |
| SCHEMBL24933053 | 0.86 | KDM4E (0.44) | HSD17B2HSD17B1CDC7ALDH1A1GLA | |
| SCHEMBL24933771 | 0.85 | IKBKB (0.42) | HSD17B2HSD17B1ALDH1A1 | |
| SCHEMBL24933181 | 0.85 | HSD17B2 (0.41) | HSD17B2HSD17B1AKR1C3AKR1C2 | |
| SCHEMBL24933343 | 0.84 | HSD17B1 (0.39) | HSD17B2HSD17B1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |