Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 11/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 11/20 | 0.41 |
| ▸ | PARP1 | P09874 | 3/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24933605 | 0.88 | HSD17B2 (0.41) | HSD17B1HSD17B2PARP1CASP1 | |
| SCHEMBL24933312 | 0.88 | BTK (0.42) | HSD17B1HSD17B2CDC7CDK5BTK | |
| SCHEMBL24933359 | 0.86 | HSD17B2 (0.50) | HSD17B1HSD17B2CDC7BTK | |
| SCHEMBL24932950 | 0.86 | HSD17B2 (0.52) | HSD17B1HSD17B2PARP1CDC7 | |
| SCHEMBL24933771 | 0.85 | IKBKB (0.42) | HSD17B1HSD17B2PARP1CDK5CDK5R1 | |
| SCHEMBL24933343 | 0.84 | HSD17B1 (0.39) | HSD17B1HSD17B2PARP1CASP1CDK5 | |
| SCHEMBL24933053 | 0.83 | KDM4E (0.44) | HSD17B1HSD17B2PARP1CASP1CDC7 | |
| SCHEMBL24933181 | 0.82 | HSD17B2 (0.41) | HSD17B1HSD17B2PARP1CDK5CDK5R1 | |
| SCHEMBL24933333 | 0.81 | GSTP1 (0.44) | HSD17B1HSD17B2BTKCHEK2 | |
| SCHEMBL24933182 | 0.81 | HSD17B1 (0.44) | HSD17B1HSD17B2BTKCHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |