Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 4/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.34 |
| ▸ | PDE1A | P54750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24933636 | 0.83 | NPBWR1 (0.41) | NPBWR1MCHR1SMN1; SMN2PDE1BPDE1C | |
| SCHEMBL29203344 | 0.81 | KDM4E (0.34) | CYP3A4CYP2D6TSHRMAPK1CYP2C19 | |
| SCHEMBL30240868 | 0.78 | NPBWR1 (0.42) | NPBWR1MCHR1SMN1; SMN2PDE1BPDE1C | |
| SCHEMBL29203391 | 0.70 | TSHR (0.33) | TSHR | |
| SCHEMBL24933627 | 0.70 | KCNH2 (0.31) | CYP3A4CYP2D6CYP2C19PDE1BPDE1C | |
| SCHEMBL24933626 | 0.67 | NPBWR1 (0.50) | NPBWR1MCHR1SMN1; SMN2PDE1BPDE1C | |
| SCHEMBL24933635 | 0.67 | NPBWR1 (0.44) | NPBWR1MCHR1SMN1; SMN2 | |
| SCHEMBL29203463 | 0.67 | NPBWR1 (0.39) | NPBWR1MCHR1SMN1; SMN2PDE1BPDE1C | |
| SCHEMBL29967137 | 0.64 | NPBWR1 (0.43) | NPBWR1MCHR1SMN1; SMN2 | |
| SCHEMBL25521029 | 0.64 | NPBWR1 (0.43) | NPBWR1MCHR1PDE1BPDE1CPDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4373809-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | Novartis AG (CH) | 2024-05-29 | — | — | EP | disclosed |
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |