Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 10/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28948243 | 0.74 | NPBWR1 (0.44) | NPBWR1MCHR1ALDH1A1MAPTGAA | |
| SCHEMBL25521029 | 0.73 | NPBWR1 (0.43) | NPBWR1MCHR1ALDH1A1MAPTMEN1 | |
| SCHEMBL25597492 | 0.71 | TSHR (0.43) | NPBWR1ALDH1A1MAPTGAALMNA | |
| SCHEMBL25603380 | 0.71 | TSHR (0.43) | NPBWR1ALDH1A1MAPTGAALMNA | |
| SCHEMBL25521015 | 0.70 | NPBWR1 (0.43) | NPBWR1MCHR1ALDH1A1MAPTMEN1 | |
| SCHEMBL6837344 | 0.69 | NPBWR1 (0.53) | NPBWR1MCHR1ALDH1A1MAPTGAA | |
| SCHEMBL30875225 | 0.68 | NPBWR1 (0.49) | NPBWR1MCHR1ALDH1A1MAPTMEN1 | |
| SCHEMBL30875221 | 0.68 | NPBWR1 (0.49) | NPBWR1MCHR1ALDH1A1MAPTMEN1 | |
| SCHEMBL24933636 | 0.68 | NPBWR1 (0.41) | NPBWR1MCHR1ALDH1A1SIGMAR1SMN1; SMN2 | |
| SCHEMBL34469279 | 0.68 | MAOA (0.39) | ALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260180-B | Triazole condensed ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-115260180-A | Triazole fused ring containing derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-11-01 | — | — | CN | disclosed |