Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24934079 | 0.85 | PYGM (0.40) | RORC | |
| SCHEMBL29218255 | 0.81 | ROCK2 (0.40) | — | |
| SCHEMBL30162743 | 0.81 | ROCK2 (0.40) | — | |
| SCHEMBL24933684 | 0.81 | KIT (0.30) | RORC | |
| SCHEMBL24934327 | 0.75 | — | — | |
| SCHEMBL24934259 | 0.71 | ABCG2 (0.41) | RORC | |
| SCHEMBL24934233 | 0.69 | SCN9A (0.41) | RORC | |
| SCHEMBL29218289 | 0.68 | NPC1 (0.46) | — | |
| SCHEMBL30162997 | 0.68 | NPC1 (0.46) | — | |
| SCHEMBL24934332 | 0.66 | RORC (0.34) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009475-A1 | ROCK2 INHIBITORS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-02-02 | — | — | WO | disclosed |