SCHEMBL24933951

SCHEMBL24933951

CC(C)c1nn(C(C)C)c2sccc12

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 1/20 0.36
MPO P05164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25077760 0.77 ADORA1 (0.50) ADORA1
SCHEMBL13708517 0.67 MPO (0.42) ADORA1MPO
SCHEMBL18212234 0.63 PIK3CG (0.39) MPO
SCHEMBL17195552 0.63 KDM4E (0.33)
SCHEMBL23937806 0.63 HTR2A (0.34) ADORA1
SCHEMBL17229789 0.62 RBP4 (0.42)
SCHEMBL18212231 0.62 ESR1 (0.41) MPO
SCHEMBL17195540 0.62 NLRP3 (0.43)
SCHEMBL17229794 0.62 SYK (0.36)
SCHEMBL23960265 0.61 RET (0.36) ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023009475-A1 ROCK2 INHIBITORS AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-02-02 WO disclosed