Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.56 |
| ▸ | RAB9A | P51151 | 9/20 | 0.56 |
| ▸ | SNCA | P37840 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | PLG | P00747 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | PLAT | P00750 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13348769 | 0.82 | F10 (0.52) | NPC1RAB9ASNCASMN1; SMN2KMT2A | |
| SCHEMBL24935800 | 0.82 | NPC1 (0.49) | NPC1RAB9ASNCASMN1; SMN2KMT2A | |
| SCHEMBL6562864 | 0.79 | MAOB (0.46) | NPC1RAB9ASMN1; SMN2MAPTAKR1C3 | |
| SCHEMBL10178435 | 0.79 | MAPT (0.51) | NPC1RAB9ASMN1; SMN2KMT2ALMNA | |
| SCHEMBL8361564 | 0.78 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL13348752 | 0.78 | MAPT (0.52) | NPC1RAB9ASMN1; SMN2KMT2ALMNA | |
| SCHEMBL13719113 | 0.77 | RAB9A (0.85) | NPC1RAB9ASMN1; SMN2KMT2ALMNA | |
| SCHEMBL6490621 | 0.77 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2KMT2ALMNA | |
| SCHEMBL17664551 | 0.76 | MEN1 (0.56) | NPC1RAB9ASMN1; SMN2KMT2ALMNA | |
| SCHEMBL13581604 | 0.76 | MEN1 (0.83) | NPC1RAB9ASMN1; SMN2KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119546-A1 | BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Suzhou Kintor Pharmaceuticals, Inc. (CN) | 2023-01-18 | — | — | EP | disclosed |