Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1951639 | 0.88 | AKR1C3 (0.51) | RAB9AAKR1C3AKR1C2MAPK1AKR1B10 | |
| SCHEMBL19331714 | 0.88 | RAB9A (0.55) | MAOBCES2CES1MAOAMAPT | |
| SCHEMBL13100225 | 0.86 | DGAT1 (0.56) | CES2CES1NPC1MAPTRAB9A | |
| SCHEMBL31003344 | 0.83 | KMT2A (0.44) | CES2CES1NPC1MAPTRAB9A | |
| SCHEMBL838252 | 0.83 | KDM4E (0.50) | MAPTRAB9AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL24619359 | 0.83 | HDAC6 (0.46) | MAOBALDH1A1MAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL7928045 | 0.83 | KDM4E (0.54) | MAOBNPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL29669896 | 0.82 | CES2 (0.67) | MAOBCES2CES1MAOANPC1 | |
| SCHEMBL75801 | 0.82 | CES2 (0.67) | MAOBCES2CES1MAOANPC1 | |
| SCHEMBL9820914 | 0.81 | PTPN1 (0.52) | MAOBMAOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9782745-B2 | Metal organic framework, production and use thereof | UTI LIMITED PARTNERSHIP (CA) | 2017-10-10 | — | — | US | disclosed |
| US-20160016148-A1 | METAL ORGANIC FRAMEWORK, PRODUCTION AND USE THEREOF | UTI LIMITED PARTNERSHIP (CA) | 2016-01-21 | — | — | US | disclosed |
| WO-2014138878-A1 | METAL ORGANIC FRAMEWORK, PRODUCTION AND USE THEREOF | UTI LIMITED PARTNERSHIP (CA) | 2014-09-18 | — | — | WO | disclosed |
| EP-1296945-B1 | SULFONAMIDE DERIVATIVES | LILLY CO ELI (US) | 2004-08-04 | — | — | EP | disclosed |
| US-6703425-B2 | ADMINISTERING GLUTAMATE RECEPTOR POTENTIATOR TO TREAT PSYCHOLOGICAL AND NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY | 2004-03-09 | — | — | US | disclosed |
| US-20030229102-A1 | Sulfonamide derivatives | ELI LILLY AND COMPANY | 2003-12-11 | — | — | US | disclosed |
| EP-1296945-A1 | SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2003-04-02 | — | — | EP | disclosed |
| WO-2001096289-A1 | SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016148-A1 | METAL ORGANIC FRAMEWORK, PRODUCTION AND USE THEREOF | SLC39A3, AOC3, SLC39A14 | MAOB 108/4885CES2 3521/4885CES1 3750/4885 |
| US-20030229102-A1 | Sulfonamide derivatives | GRIN1, GRIN2A, SLC1A2 | MAOB 1099/4885CES2 514/4885CES1 1083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.