Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.50 |
| ▸ | F10 | P00742 | 2/20 | 0.50 |
| ▸ | PLAU | P00749 | 2/20 | 0.50 |
| ▸ | PLAT | P00750 | 2/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GCGR | P47871 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6500905 | 0.89 | TRPV1 (0.50) | NPC1RAB9ASMN1; SMN2TP53LMNA | |
| SCHEMBL6502779 | 0.82 | HDAC7 (0.51) | NPC1RAB9ASMN1; SMN2F2F10 | |
| SCHEMBL13719113 | 0.78 | RAB9A (0.85) | NPC1RAB9AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL24934728 | 0.77 | NPC1 (0.56) | NPC1RAB9AMAPTSMN1; SMN2F2 | |
| SCHEMBL7372972 | 0.75 | CHRNB2 (0.63) | NPC1RAB9AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL6490383 | 0.75 | PTGS1 (0.58) | NPC1RAB9ASMN1; SMN2TP53LMNA | |
| SCHEMBL6795828 | 0.74 | CHRNB2 (0.57) | NPC1RAB9AMAPTSMN1; SMN2F10 | |
| SCHEMBL14003411 | 0.74 | HSD17B1 (0.57) | NPC1RAB9AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL17066707 | 0.73 | RAB9A (0.88) | NPC1RAB9AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL15214314 | 0.73 | RAB9A (0.88) | NPC1RAB9AMAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | NPC1 100/4885RAB9A 4382/4885MAPT 4202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.