Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24934383 | 1.00 | PDK2 (0.44) | PDK2PDK1 | |
| SCHEMBL24934377 | 0.89 | PDK2 (0.43) | PDK2PDK1 | |
| SCHEMBL24934380 | 0.89 | PDK2 (0.43) | PDK2PDK1 | |
| SCHEMBL24934624 | 0.89 | PDK2 (0.43) | PDK2PDK1 | |
| SCHEMBL24860275 | 0.88 | PDK2 (0.43) | PDK2PDK1 | |
| SCHEMBL24934794 | 0.88 | PDK2 (0.43) | PDK2PDK1 | |
| SCHEMBL24934658 | 0.87 | PDK2 (0.42) | PDK2PDK1 | |
| SCHEMBL24934860 | 0.87 | PDK2 (0.42) | PDK2PDK1 | |
| SCHEMBL24934563 | 0.87 | PDK2 (0.46) | PDK2PDK1 | |
| SCHEMBL24934659 | 0.87 | PDK2 (0.42) | PDK2PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230025880-A1 | FUSED TRICYCLIC COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2023-01-26 | — | — | US | disclosed |
| CN-115151543-A | Fused tricyclic compounds and medical use thereof | 日本烟草产业株式会社 | 2022-10-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230025880-A1 | FUSED TRICYCLIC COMPOUND AND MEDICINAL USE THEREOF | PC, PCK2, AGK | PDK2 4/4885PDK1 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.