Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 8/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | RHEB | Q15382 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24935779 | 0.87 | AR (0.36) | PPARDHPGDKDM4ERAB9AALDH1A1 | |
| SCHEMBL24935608 | 0.85 | PPARG (0.36) | PPARDHPGDCDK8KDM4ERAB9A | |
| SCHEMBL24935357 | 0.81 | HDAC1 (0.44) | PPARDHPGDKDM4ERAB9AALDH1A1 | |
| SCHEMBL24935694 | 0.79 | L3MBTL1 (0.42) | HPGDCYP1A2CYP2C9CYP2C19MAOB | |
| SCHEMBL24935009 | 0.77 | PPARD (0.37) | PPARDHPGDCDK8KDM4ERAB9A | |
| SCHEMBL18644413 | 0.76 | CYP17A1 (0.36) | PPARDCDK8CYP2C9CYP2C19RHEB | |
| SCHEMBL25063751 | 0.75 | S1PR1 (0.36) | PPARDHPGDKDM4ERAB9AMAOA | |
| SCHEMBL16723455 | 0.74 | LMNA (0.46) | PPARDCYP2C9CYP2C19RHEBHTT | |
| SCHEMBL5543083 | 0.74 | MCL1 (0.56) | PPARDHPGDKDM4EALDH1A1MAPT | |
| SCHEMBL12059085 | 0.72 | TSHR (0.50) | KDM4ECYP1A2HTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119546-A1 | BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Suzhou Kintor Pharmaceuticals, Inc. (CN) | 2023-01-18 | — | — | EP | disclosed |