Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RHEB | Q15382 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | AGER | Q15109 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24935357 | 0.85 | HDAC1 (0.44) | PPARDKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL24935232 | 0.77 | PPARD (0.38) | PPARDKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL24935608 | 0.77 | PPARG (0.36) | PPARDKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL25063888 | 0.75 | KDM4E (0.36) | PPARDKDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL5543083 | 0.74 | MCL1 (0.56) | PPARDKDM4EALDH1A1HPGDAGER | |
| SCHEMBL24935607 | 0.72 | MRGPRX4 (0.41) | KDM4EALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL24935148 | 0.72 | L3MBTL1 (0.45) | CYP1A2CYP2C9HPGDCYP2C19 | |
| SCHEMBL12844962 | 0.69 | THRA (0.39) | PPARDCYP1A2CYP2C9CYP2C19RHEB | |
| SCHEMBL12778374 | 0.69 | PDK2 (0.43) | PPARDALDH1A1CYP1A2CYP2C19THRA | |
| SCHEMBL14778080 | 0.69 | ACHE (0.54) | KDM4EALDH1A1RHEBEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119546-A1 | BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Suzhou Kintor Pharmaceuticals, Inc. (CN) | 2023-01-18 | — | — | EP | disclosed |