Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14996240 | 0.91 | TSHR (0.43) | TSHRHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL21016081 | 0.90 | FAAH (0.45) | TSHRHPGDALDH1A1NAMPTCASP2 | |
| SCHEMBL14996245 | 0.90 | TSHR (0.44) | TSHRHPGDLMNAPKMALDH1A1 | |
| SCHEMBL25063763 | 0.85 | HPGD (0.43) | TSHRHPGDLMNAPKMALDH1A1 | |
| SCHEMBL21947703 | 0.85 | TSHR (0.73) | TSHRHPGDLMNAPKMALDH1A1 | |
| SCHEMBL20022933 | 0.83 | TSHR (0.59) | TSHRHPGDLMNAPKMALDH1A1 | |
| SCHEMBL6957597 | 0.82 | SMN1; SMN2 (0.48) | HPGDLMNAPKMALDH1A1CNR1 | |
| SCHEMBL23729303 | 0.82 | TSHR (0.64) | TSHRHPGDLMNAPKMALDH1A1 | |
| SCHEMBL24935618 | 0.82 | HPGD (0.43) | TSHRHPGDLMNAPKMALDH1A1 | |
| SCHEMBL23945670 | 0.81 | EPHX2 (0.40) | TSHRALDH1A1FAAHRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119546-A1 | BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Suzhou Kintor Pharmaceuticals, Inc. (CN) | 2023-01-18 | — | — | EP | disclosed |