Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | CNR1 | P21554 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21947703 | 0.91 | TSHR (0.73) | TSHRHPGDCNR1LMNAPKM | |
| SCHEMBL17620529 | 0.89 | TSHR (0.53) | TSHRHPGDCNR1HTTSMN1; SMN2 | |
| SCHEMBL12834880 | 0.86 | TSHR (0.59) | TSHRHPGDCNR1HTTSMN1; SMN2 | |
| SCHEMBL23729303 | 0.85 | TSHR (0.64) | TSHRHPGDCNR1HTTSMN1; SMN2 | |
| SCHEMBL12934640 | 0.85 | TSHR (0.69) | TSHRHPGDCNR1HTTSMN1; SMN2 | |
| SCHEMBL25480646 | 0.84 | TSHR (0.54) | TSHRHPGDCNR1HTTSMN1; SMN2 | |
| SCHEMBL18707765 | 0.84 | HPGD (0.49) | TSHRHPGDCNR1HTTSMN1; SMN2 | |
| SCHEMBL24935539 | 0.83 | TSHR (0.51) | TSHRHPGDCNR1LMNAPKM | |
| SCHEMBL18707764 | 0.83 | HPGD (0.48) | TSHRHPGDCNR1HTTSMN1; SMN2 | |
| SCHEMBL25532038 | 0.83 | TSHR (0.47) | TSHRHPGDCNR1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827744-B2 | Bottlebrush copolymers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-11-28 | — | — | US | disclosed |
| US-20180094099-A1 | BOTTLEBRUSH COPOLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180094099-A1 | BOTTLEBRUSH COPOLYMERS AND USES THEREOF | TRIB1, TRIB2, ABCB11 | TSHR 777/4885HPGD 773/4885CNR1 636/4885 |
| US-11827744-B2 | Bottlebrush copolymers and uses thereof | TRIB1, TRIB2, ABCB11 | TSHR 777/4885HPGD 773/4885CNR1 636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.