SCHEMBL24935549

SCHEMBL24935549

COCCCOCCOc1ccc(C(C)=O)cc1

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.67
GAA P10253 1/20 0.65
MAPT P10636 5/20 0.56
ALDH1A1 P00352 1/20 0.56
RARB P10826 1/20 0.55
LMNA P02545 1/20 0.49
POLB P06746 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
MAOB P27338 4/20 0.48
HRH2 P25021 1/20 0.47
HRH1 P35367 1/20 0.47
HRH3 Q9Y5N1 2/20 0.47
KDM4E B2RXH2 1/20 0.47
RAB9A P51151 2/20 0.46
HPGD P15428 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24935614 0.97 L3MBTL1 (0.72) L3MBTL1GAAMAPTALDH1A1RARB
SCHEMBL13894709 0.92 L3MBTL1 (0.68) L3MBTL1GAAMAPTALDH1A1RARB
SCHEMBL4445351 0.92 L3MBTL1 (0.68) L3MBTL1GAAMAPTALDH1A1RARB
SCHEMBL8672706 0.88 L3MBTL1 (0.78) L3MBTL1GAAMAPTALDH1A1RARB
SCHEMBL24935612 0.87 GAA (0.86) L3MBTL1GAAMAPTALDH1A1RARB
SCHEMBL933535 0.87 L3MBTL1 (0.75) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL13350009 0.86 PARP10 (0.59) L3MBTL1GAAMAPTRARBHRH3
SCHEMBL12252924 0.86 L3MBTL1 (0.69) L3MBTL1GAAMAPTALDH1A1RARB
SCHEMBL10262507 0.85 L3MBTL1 (0.59) L3MBTL1GAAMAPTALDH1A1RARB
SCHEMBL15223679 0.85 PLK1 (0.63) L3MBTL1GAAMAPTALDH1A1RARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4119546-A1 BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF Suzhou Kintor Pharmaceuticals, Inc. (CN) 2023-01-18 EP disclosed