SCHEMBL933535

SCHEMBL933535

COCCOc1ccc(C(C)=O)cc1

nearest known ligand 0.75

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.75
GAA P10253 1/20 0.72
MAPT P10636 6/20 0.67
ALDH1A1 P00352 1/20 0.67
LMNA P02545 1/20 0.58
POLB P06746 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
RAB9A P51151 2/20 0.55
HPGD P15428 1/20 0.55
MAOB P27338 7/20 0.54
PKM P14618 1/20 0.52
MAOA P21397 1/20 0.51
HRH3 Q9Y5N1 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30837212 0.95 L3MBTL1 (0.68) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL13894709 0.95 L3MBTL1 (0.68) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL4445351 0.95 L3MBTL1 (0.68) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL834525 0.92 L3MBTL1 (0.88) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL14579704 0.90 L3MBTL1 (0.62) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL24935612 0.89 GAA (0.86) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL7186388 0.87 L3MBTL1 (0.62) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL24935549 0.87 L3MBTL1 (0.67) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL24935614 0.87 L3MBTL1 (0.72) L3MBTL1GAAMAPTALDH1A1LMNA
SCHEMBL12455672 0.86 MAPT (0.63) L3MBTL1GAAMAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4658656-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES Beone Medicines I GmbH (CH) 2025-12-10 EP disclosed
US-20250346597-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES BEONE MEDICINES I GMBH (CH) 2025-11-13 US disclosed
US-20240279231-A1 MAP4K4 INHIBITORS AND METHODS OF SYNTHESIS AND USE THEREOF THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) 2024-08-22 US disclosed
WO-2024160276-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES BEIGENE, LTD. (KY) 2024-08-08 WO disclosed
US-11208397-B2 Small molecule antagonists of sumo related modification of CRMP2 and uses thereof ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2021-12-28 US disclosed
US-20200277271-A1 SMALL MOLECULE ANTAGONISTS OF SUMO RELATED MODIFICATION OF CRMP2 AND USES THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA 2020-09-03 US disclosed
WO-2018144900-A1 SMALL MOLECULE ANTAGONISTS OF SUMO RELATED MODIFICATION OF CRMP2 AND USES THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2018-08-09 WO disclosed
US-9957281-B2 Benzodiazepine derivatives as RSV inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2018-05-01 US disclosed
US-20170022221-A1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS ENANTA PHARMACEUTICALS, INC. 2017-01-26 US disclosed
US-8313814-B2 Cellulose acylate film, method of producing the same, cellulose derivative film, optically compensatory film using the same, optically-compensatory film incorporating polarizing plate, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-11-20 US disclosed
WO-2007086599-A1 LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2007-08-02 WO disclosed
WO-2007086538-A1 RETARDATION PLATE, POLARIZER PLATE, AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPOTATION (JP) 2007-08-02 WO disclosed
WO-2007037539-A9 CELLULOSE DERIVATIVE FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DEVICE FUJIFILM CORP (JP) 2007-05-31 WO disclosed
WO-2007037539-A1 CELLULOSE DERIVATIVE FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DEVICE FUJIFILM CORPORATION (JP) 2007-04-05 WO disclosed
WO-2007023990-A1 LIQUID CRYSTAL DISPLAY DEVICE FUJI FILM CORPORATION (JP) 2007-03-01 WO disclosed
US-20040171516-A1 Precursors for ketones and aldehydes GIVAUDAN SA (CH) 2004-09-02 US disclosed
EP-1390337-A1 PRECURSORS FOR KETONES AND ALDEHYDES Givaudan SA (CH) 2004-02-25 EP disclosed
WO-2002096850-A1 PRECURSORS FOR KETONES AND ALDEHYDES GIVAUDAN SA (CH) 2002-12-05 WO disclosed
EP-1262473-A1 Precursors for fragrant ketones and fragrant aldehydes Givaudan SA (CH) 2002-12-04 EP disclosed
EP-0030030-A1 Derivatives of 2-aminoethanol, processes for their preparation, pharmaceutical compositions containing such compounds and the use the latter CIBA-GEIGY AG (CH) 1981-06-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240279231-A1 MAP4K4 INHIBITORS AND METHODS OF SYNTHESIS AND USE THEREOF MAP4K4, MAP4K2, MAPK4 L3MBTL1 4474/4885GAA 3828/4885MAPT 141/4885
US-11208397-B2 Small molecule antagonists of sumo related modification of CRMP2 and uses thereof SUMO2, SUMO1, SUMO3 L3MBTL1 4080/4885GAA 4309/4885MAPT 1743/4885
US-20250346597-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES DGKG, DGKA, DGKK L3MBTL1 4317/4885GAA 1551/4885MAPT 4168/4885
US-20200277271-A1 SMALL MOLECULE ANTAGONISTS OF SUMO RELATED MODIFICATION OF CRMP2 AND USES THEREOF SUMO2, SUMO1, SUMO3 L3MBTL1 4080/4885GAA 4309/4885MAPT 1743/4885
US-20170022221-A1 BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS GABRA5, GABRA1, GABBR2 L3MBTL1 4773/4885GAA 1755/4885MAPT 2157/4885
US-20040171516-A1 Precursors for ketones and aldehydes PDK3, PDK4, AKR1C4 L3MBTL1 4439/4885GAA 1922/4885MAPT 3633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.