Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 3/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | PTGIR | P43119 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24935582 | 0.85 | ACACB (0.38) | ACACBNR1I2ADORA3DRD1TBXA2R | |
| SCHEMBL25063728 | 0.82 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10ACACBMAPT | |
| SCHEMBL19599653 | 0.77 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10ACACBADORA3 | |
| SCHEMBL19598479 | 0.76 | SMN1; SMN2 (0.36) | KDM4EALDH1A1ACACBMAPTRAB9A | |
| SCHEMBL19598472 | 0.75 | DGAT1 (0.42) | ACACBNR1I2ADORA3DRD1TBXA2R | |
| SCHEMBL14182464 | 0.72 | CYP3A4 (0.50) | KDM4EALDH1A1HSD17B10MAPTRAB9A | |
| SCHEMBL11929545 | 0.72 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10MAPTHCRTR2 | |
| SCHEMBL21241067 | 0.71 | KDM4E (0.41) | KDM4EALDH1A1HSD17B10ACACBMAPT | |
| SCHEMBL13412644 | 0.71 | CYP3A4 (0.52) | KDM4EALDH1A1HSD17B10NR1I2MAPT | |
| SCHEMBL10265614 | 0.71 | ALDH1A1 (0.49) | KDM4EALDH1A1HSD17B10MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119546-A1 | BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Suzhou Kintor Pharmaceuticals, Inc. (CN) | 2023-01-18 | — | — | EP | disclosed |