Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24935781 | 0.82 | MRGPRX4 (0.41) | MAPTALDH1A1MRGPRX4L3MBTL1SMN1; SMN2 | |
| SCHEMBL14293809 | 0.81 | MAPT (0.50) | MAPTALDH1A1POLBGPR55MRGPRX4 | |
| SCHEMBL24935186 | 0.80 | MRGPRX4 (0.44) | MAPTALDH1A1POLBGPR55MRGPRX4 | |
| SCHEMBL20207970 | 0.76 | MRGPRX4 (0.43) | MAPTALDH1A1POLBMRGPRX4L3MBTL1 | |
| SCHEMBL8361632 | 0.76 | MAPT (0.47) | MAPTALDH1A1POLBGPR55MRGPRX4 | |
| SCHEMBL15004597 | 0.75 | APP (0.43) | MAPTALDH1A1POLBMRGPRX4L3MBTL1 | |
| SCHEMBL13478850 | 0.75 | MAPT (0.52) | MAPTALDH1A1MRGPRX4L3MBTL1TDP1 | |
| SCHEMBL24935607 | 0.74 | MRGPRX4 (0.41) | ALDH1A1MRGPRX4SMN1; SMN2TDP1KDM4E | |
| SCHEMBL18896188 | 0.73 | THRB (0.52) | MAPTALDH1A1MRGPRX4L3MBTL1TDP1 | |
| SCHEMBL12017785 | 0.73 | MRGPRX4 (0.44) | MAPTALDH1A1MRGPRX4L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119546-A1 | BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Suzhou Kintor Pharmaceuticals, Inc. (CN) | 2023-01-18 | — | — | EP | disclosed |