Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.34 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24935781 | 0.90 | MRGPRX4 (0.41) | MRGPRX4FFAR1CYP2C9TDP1SMN1; SMN2 | |
| SCHEMBL24935609 | 0.85 | FFAR1 (0.37) | MRGPRX4AAK1FFAR1ALDH1A1 | |
| SCHEMBL24934755 | 0.76 | MRGPRX4 (0.41) | MRGPRX4AAK1FFAR1SMN1; SMN2HPGD | |
| SCHEMBL25063906 | 0.74 | FFAR1 (0.37) | MRGPRX4AAK1FFAR1KDM4E | |
| SCHEMBL24935653 | 0.74 | MAPT (0.36) | MRGPRX4CYP2C9TDP1SMN1; SMN2TTR | |
| SCHEMBL24935230 | 0.73 | MRGPRX4 (0.46) | MRGPRX4FFAR1PTGDR2 | |
| SCHEMBL24935659 | 0.73 | MRGPRX4 (0.44) | MRGPRX4FFAR1SMN1; SMN2TSHRPTGDR2 | |
| SCHEMBL27051686 | 0.73 | MRGPRX4 (0.41) | MRGPRX4AAK1FFAR1CYP2C9ALDH1A1 | |
| SCHEMBL24935148 | 0.73 | L3MBTL1 (0.45) | CYP2C9CYP1A2PPARAHPGD | |
| SCHEMBL24935009 | 0.72 | PPARD (0.37) | CYP2C9CYP1A2KDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119546-A1 | BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Suzhou Kintor Pharmaceuticals, Inc. (CN) | 2023-01-18 | — | — | EP | disclosed |