Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9945951 | 0.89 | HTT (0.41) | L3MBTL1ALDH1A1LMNATHRATHRB | |
| SCHEMBL15000495 | 0.88 | THRA (0.49) | L3MBTL1ALDH1A1LMNATHRATHRB | |
| SCHEMBL20225798 | 0.88 | THRA (0.49) | L3MBTL1ALDH1A1LMNATHRATHRB | |
| SCHEMBL11994372 | 0.88 | FAAH (0.43) | L3MBTL1ALDH1A1LMNATHRATHRB | |
| SCHEMBL25063748 | 0.87 | L3MBTL1 (0.39) | L3MBTL1ALDH1A1LMNATHRATHRB | |
| SCHEMBL23178692 | 0.84 | KDM4E (0.39) | L3MBTL1MRGPRX4HTTSMN1; SMN2FFAR1 | |
| SCHEMBL20232153 | 0.82 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1LMNATHRATHRB | |
| SCHEMBL24935186 | 0.80 | MRGPRX4 (0.44) | L3MBTL1ALDH1A1THRATHRBMRGPRX4 | |
| SCHEMBL8228423 | 0.79 | KDM1A (0.47) | L3MBTL1ALDH1A1MRGPRX4TDP1FAAH | |
| SCHEMBL25063933 | 0.79 | MRGPRX4 (0.40) | L3MBTL1ALDH1A1LMNATHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119546-A1 | BIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | Suzhou Kintor Pharmaceuticals, Inc. (CN) | 2023-01-18 | — | — | EP | disclosed |