Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19362277 | 0.89 | SOS1 (0.34) | SOS1SOS2 | |
| SCHEMBL19362275 | 0.80 | TSHR (0.35) | SOS1SOS2 | |
| SCHEMBL22430312 | 0.78 | SOS1 (0.32) | SOS1SOS2 | |
| SCHEMBL27806671 | 0.78 | MEN1 (0.33) | MEN1KMT2AGNAI3GNAO1GNAI1 | |
| SCHEMBL22430354 | 0.77 | SOS1 (0.30) | SOS1SOS2 | |
| SCHEMBL24936392 | 0.77 | ALOX15 (0.31) | SOS1SOS2 | |
| SCHEMBL22430310 | 0.76 | SOS1 (0.32) | SOS1SOS2 | |
| SCHEMBL9236814 | 0.75 | GNAO1 (0.34) | MEN1KMT2AGNAI3GNAO1GNAI1 | |
| SCHEMBL7025044 | 0.74 | MEN1 (0.31) | MEN1KMT2AGNAI3GNAO1GNAI1 | |
| SCHEMBL22430386 | 0.74 | GNAI3 (0.32) | GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3430017-B1 | COMPOSITIONS AND METHODS FOR TREATING PARASITIC DISEASES | UNIV CALIFORNIA (US) | 2023-01-25 | — | — | EP | disclosed |