Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.43 |
| ▸ | RELA | Q04206 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27774480 | 0.85 | MEN1 (0.53) | MEN1KMT2AALDH1A1NFKB1NFKB2 | |
| SCHEMBL12086366 | 0.84 | KMT2A (0.51) | MEN1KMT2AALDH1A1NFKB1NFKB2 | |
| SCHEMBL27578920 | 0.84 | MEN1 (0.51) | MEN1KMT2AALDH1A1NFKB1NFKB2 | |
| SCHEMBL27766267 | 0.83 | KMT2A (0.50) | MEN1KMT2AALDH1A1NFKB1NFKB2 | |
| SCHEMBL28868300 | 0.83 | MEN1 (0.44) | MEN1KMT2AALDH1A1NFKB1NFKB2 | |
| SCHEMBL27445939 | 0.82 | CYP3A4 (0.45) | MEN1KMT2AALDH1A1BCHETSHR | |
| SCHEMBL28941287 | 0.81 | LMNA (0.42) | MEN1KMT2AALDH1A1NFKB1NFKB2 | |
| SCHEMBL6189602 | 0.80 | KMT2A (0.47) | MEN1KMT2AALDH1A1NFKB1NFKB2 | |
| SCHEMBL28941154 | 0.80 | MEN1 (0.41) | MEN1KMT2AALDH1A1NFKB1NFKB2 | |
| SCHEMBL19439086 | 0.80 | MEN1 (0.81) | MEN1KMT2AALDH1A1NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111051309-B | Triazolotriazine derivatives useful as A2A receptor antagonists | 浙江春禾医药科技有限公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-101678215-B | Sulfonamide derivatives for the treatment of abnormal cell growth | PFIZER PRODUCTS INC. (US) | 2014-10-01 | — | — | CN | disclosed |
| CN-103951658-A | Sulfonyl amide derivatives for the treatment of abnormal cell growth | PFIZER PROD INC | 2014-07-30 | — | — | CN | disclosed |
| EP-1518855-B1 | DIAMINOPYRIMIDINECARBOXA MIDE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2011-10-26 | — | — | EP | disclosed |
| CN-101678215-A | Sulfonamide derivatives for the treatment of abnormal cell growth | PFIZER PROD INC | 2010-03-24 | — | — | CN | disclosed |